Research

There are 3 types of research and testing under the center.

1) Biomedical research using cynomolgus macaques (Macaca fascicularis) as animal models in ABSL1 or 2 facility in the center, including

  • Pharmacokinetics of insulin, parathyroid hormone, erythropoietin, growth hormone and Thai herbal extract.
  • Microbiome
  • Safety and efficacy test of Dengue and Zika vaccine
  • Safety test of COVID-19 vaccine
  • Spinal subpial AAV delivery
  • Behaviors

2) Field study which has been conducted in free-ranging monkeys outside the NPRCT-CU.

  • 2.1. Infectious diseases in cynomolgus and rhesus macaques (Macaca mulatta), including
    • Microbiome
    • Tuberculosis
    • Malaria
    • Viruses such as B-virus, SIV, SRV, STLV, and flavivirus
    • Enteric parasites and bacteria
  • 2.2. Genetic diversity of rhesus macaques and the two subspecies of long-tailed macaques (Macaca fascicularis fascicularis and M. f. aurea), including
    • Whole genome sequencing
    • Population genetics
    • Major histocompatibility complex (MHC) diversity
  • 2.3. Reproduction and behaviors in stump-tailed macaques (M. arctoides) and Burmese long-tailed macaques (M. f. aurea)

3) Behavioral and cognitive neuroscience investigating behaviors and cognition of in-house as well as free-ranging monkeys with 3 main focuses

  • Tool use and cognitive flexibility
  • Social cognition and intelligence
  • Behavioral management of captive NHPs